Effect of Roflumilast on Airway Blood Flow as an Expression of Airway Inflammation in COPD

Summary

The objectives of the proposed study are to determine 1) the effect of a single dose of Roflumilast on airway blood flow (Qaw) (study period 1) and 2) the effect of long-term Roflumilast treatment on airway blood flow reactivity delta Qaw)(study period 2) in patients with stable COPD who use ICS regularly.

Timeline

Start

2013-02

Primary completion

2015-07

Completion

2015-07

Drugs

Indications