drugset / Trial / NCT02099396

A Clinical Trial on Efficacy and Safety for Lobaplatin and Gemcitabine in Combination With Docetaxel in the Second-line Treatments on Advanced Osteosarcoma

NCT02099396

Phase 2/3 Unknown 100 enrolled China Association of Osteosarcoma Chemotherapy
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose was to evaluate efficacy, safety and effects on survival for lobaplatin and Gemcitabine in combination with Docetaxel, which can provide a kind of completely new second-line chemotherapy program for osteosarcoma patients in aggressive-phase, provide accurate and reliable evidence-based results for clinical applications of lobaplatin in osteosarcoma patients as one of the third-generation of platinum drugs, and further consummate and enrich clinical practice guidance on osteosarcoma all over the world.

Timeline

Start
2014-04
Primary completion
2016-06
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 675 mg/m2 Intravenous
Subject Lobaplatin Small molecule 30 mg/m2 Intravenous
Background Docetaxel Small molecule 75 mg/m2 Intravenous

Indications

No indication recorded.