drugset / Trial / NCT02100852

TGR-1202, a PI3K Delta Inhibitor, in Combination With Obinutuzumab and Chlorambucil in Patients With Chronic Lymphocytic Leukemia (CLL)

NCT02100852

Phase 1 Completed 19 enrolled TG Therapeutics, Inc.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and effectiveness of TGR-1202 in combination with obinutuzumab (Gazyva) and chlorambucil in patients with chronic lymphocytic leukemia.

Timeline

Start
2014-03-12
Primary completion
2017-11
Completion
2017-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Umbralisib Small molecule Oral
Background Chlorambucil Other / unclassified Oral
Background Obinutuzumab Monoclonal antibody Intravenous