drugset / Trial / NCT02101905

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

NCT02101905

Phase 1 Completed 29 enrolled National Cancer Institute (NCI)
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This pilot phase I clinical trial studies how well lapatinib ditosylate before surgery works in treating patients with high-grade glioma that has come back after a period of time during which the tumor could not be detected. Lapatinib ditosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2016-11-07
Primary completion
2021-10-19
Completion
2024-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Lapatinib Small molecule Oral