Probing the Cannabinoid System in Individuals With a Family History of Psychosis

Summary

The overall purpose of this study is to determine whether a family history of psychosis is associated with an altered cannabinoid system. This will be tested by studying individuals with and without a family history of psychosis and comparing their responses to delta 9-tetrahydrocannabinol (THC), a probe of the cannabinoid system. We hypothesize, that compared to controls with no family history of psychoses, individuals with a family history of psychoses will have an altered response to THC.

Timeline

Start

2014-01

Primary completion

2026-06

Completion

2026-12

Drugs

Indications