Phase 2 Study With Abraxane (Nab®Paclitaxel) in Metastatic Colorectal Cancer

Summary

The purpose of this study is to evaluate the safety and efficacy of Abraxane (nab-paclitaxel) in subjects with previously treated metastatic colorectal cancer. Subjects will be placed into two separate cohorts based on their RAS mutation status.

Timeline

Start

2014-05-05

Primary completion

2014-11-10

Completion

2015-01-09

Publications

• Ducreux M, Bennouna J, Adenis A, Conroy T, Lievre A, Portales F, Jeanes J, Li L, Romano A. Efficacy and safety of nab-paclitaxel in patients with previously treated metastatic colorectal cancer: a phase II COLO-001 trial. Cancer Chemother Pharmacol. 2017 Jan;79(1):9-16. doi: 10.1007/s00280-016-3193-5. Epub 2016 Nov 19.

Drugs

Indications