drugset / Trial / NCT02107885
Single Ascending Dose Study Using DS-1971 to Assess Safety, Tolerability, and Pharmacokinetics in Healthy Participants.
RandomizedParallel-groupQuadruple-blindBasic science
Summary
This is a randomised, double-blind, placebo-controlled and ascending single dose study. It is hypothesised that single oral doses of DS-1971a within the planned dose range will be safe and well tolerated by healthy male subjects.
Timeline
- Start
- 2014-03
- Primary completion
- 2014-07
- Completion
- 2014-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | DS-1971 | Small molecule | 5 mg | Oral |
| Subject | DS-1971 | Small molecule | 10 mg | Oral |
| Subject | DS-1971 | Small molecule | 30 mg | Oral |
| Subject | DS-1971 | Small molecule | 90 mg | Oral |
| Subject | DS-1971 | Small molecule | 250 mg | Oral |
| Subject | DS-1971 | Small molecule | 500 mg | Oral |
| Subject | DS-1971 | Small molecule | 1000 mg | Oral |
| Subject | DS-1971 | Small molecule | 1500 mg | Oral |
Indications
No indication recorded.