drugset / Trial / NCT02112292

The Role of the Endocannabinoid System in Sweet Taste Intensity and Liking

NCT02112292

Completed 10 enrolled Wageningen University
RandomizedCrossoverTriple-blindBasic science

Summary

The endocannabinoid (eCB) system, a neurochemical signalling system consisting of CB-receptors and their endogenous ligands, has been found to be involved in food intake of sweet and palatable foods. Activation of the eCB system increases food intake and vice versa. The mechanism behind this effect is still unknown and the current study aims at clarifying why sweet food intake increases. It is hypothesized that sweet taste intensity increases and that sweet taste is experienced as more pleasant.

Timeline

Start
2014-04
Primary completion
2015-04-16
Completion
2015-04-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Cannabidiol Other / unclassified
Subject Dronabinol Other / unclassified

Indications

No indication recorded.