drugset / Trial / NCT02113319

Study to Assess Dasatinib in Patients With Core Binding Factors Acute Myelogenous Leukemia

NCT02113319 ↗

Phase 2 Completed 27 enrolled University Hospital, Angers
NaSingle-groupOpen-labelSupportive care

Summary

In patients with Core Binding Factors Acute Myelogenous Leukemia, the level of Minimal Residual Disease after chemotherapy is predictive of relapse. The relapse risk is also increased in case of mutations of receptors tyrosine kinase. For patients with a high Minimal Residual Disease level at the end of consolidation or in molecular relapse, maintenance by the inhibitor dasatinib is proposed.

Timeline

Start
2007-04
Primary completion
2012-05
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject dasatinib anhydrous Small molecule 20 mg —
Subject dasatinib anhydrous Small molecule 50 mg —