drugset / Trial / NCT02115672

Imatinib and BL-8040 (Novel Anti CXCR4 Antagonist) for Improving Molecular Response in Chronic Myelogenous Leukemia

NCT02115672

Phase 1/2 Withdrawn Sheba Medical Center
NaSingle-groupOpen-labelTreatment

Summary

The aim of the study is to test the safety and efficacy of BL-8040 (a CXCR4 antagonist) in improving the response to imatinib in CML patients not achieving an optimal response with imatinib alone.

Timeline

Start
2014-11
Primary completion
2016-11
Completion
2018-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Motixafortide Peptide 0.5 mg/kg Subcutaneous
Subject Motixafortide Peptide 1.25 mg/kg Subcutaneous