drugset / Trial / NCT02116335
Endothelin Receptor Function and Acute Stress
Active not recruiting
320 enrolled
Augusta University
National Heart, Lung, and Blood Institute (NHLBI) · collab
RandomizedCrossoverDouble-blindTreatment
Summary
Our bodies respond differently to stress. Animal studies by the investigators have found that endothelin-1 plays a role in regulating blood pressure in response to stress. This study is an extension of the investigators previous animal work to evaluate the role of endothelin-1 during stress in humans.
Timeline
- Start
- 2015-06
- Primary completion
- 2025-12
- Completion
- 2026-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bosentan | Other / unclassified | 125 mg | — |