drugset / Trial / NCT02120703

Pregabalin Compared to Gabapentin for Pain Control in Lumbar Disc Surgery

NCT02120703

Phase 3 Completed 78 enrolled Aga Khan University
RandomizedParallel-groupSingle-blindSupportive care

Summary

Pregabalin is claimed to have superior analgesic effect at lower doses and better pharmacological profile as compared to gabapentin esp. in perioperative pain control after major surgeries like intervertebral disc surgery. The investigators found that pregabalin is equivalent to gabapentin for relief of post-operative pain at a lower dose in patients undergoing intervertebral disc surgery.

Timeline

Start
2011-02
Primary completion
2011-10
Completion
2011-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Gabapentin Small molecule 200 mg Oral
Comparator Pregabalin Small molecule 75 mg Oral

Indications