drugset / Trial / NCT02120703
Pregabalin Compared to Gabapentin for Pain Control in Lumbar Disc Surgery
RandomizedParallel-groupSingle-blindSupportive care
Summary
Pregabalin is claimed to have superior analgesic effect at lower doses and better pharmacological profile as compared to gabapentin esp. in perioperative pain control after major surgeries like intervertebral disc surgery. The investigators found that pregabalin is equivalent to gabapentin for relief of post-operative pain at a lower dose in patients undergoing intervertebral disc surgery.
Timeline
- Start
- 2011-02
- Primary completion
- 2011-10
- Completion
- 2011-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Gabapentin | Small molecule | 200 mg | Oral |
| Comparator | Pregabalin | Small molecule | 75 mg | Oral |