drugset / Trial / NCT02124746

Long-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia

NCT02124746

Phase 2 Completed 87 enrolled Sierra Oncology LLC - a GSK company
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This open-label study is to determine the long-term safety and tolerability of momelotinib in previously enrolled study participants with primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (post-PV MF), post-essential thrombocythemia myelofibrosis (post-ET MF), polycythemia vera (PV), or essential thrombocythemia (ET), who have tolerated and achieved stable disease or better with momelotinib treatment while enrolled in a previous clinical trial.

Timeline

Start
2014-04-30
Primary completion
2018-12-06
Completion
2018-12-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Momelotinib Small molecule Oral