drugset / Trial / NCT02126969

A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN

NCT02126969 ↗

Phase 2 Completed 45 enrolled Susanne Arnold
RandomizedParallel-groupSingle-blindTreatment

Summary

The primary hypothesis of this study is that hyper-radiosensitivity (HRS) seen at extremely low doses of radiation can be exploited to enhance the effect of chemotherapy, and that this effect differs from the cellular effect of higher, standard fractions of radiation used in traditional radiation treatment paradigms.

Timeline

Start
2014-10
Primary completion
2018-03
Completion
2021-06-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Carboplatin Small molecule 6 unknown —
Comparator Docetaxel Small molecule 75 mg/m2 —