drugset / Trial / NCT02127034
Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects
RandomizedCrossoverOpen-labelBasic science
Summary
The purpose of this study is to evaluate the effect of steady state solifenacin and mirabegron on the pharmacokinetics of co-administered steady state digoxin. This study will also evaluate the safety and tolerability of the combined steady state administration of solifenacin, mirabegron and digoxin.
Timeline
- Start
- 2014-03
- Primary completion
- 2014-06
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Digoxin | Other / unclassified | — | Oral |
| Subject | Mirabegron | Other / unclassified | — | Oral |
| Subject | Solifenacin | Small molecule | — | Oral |
Indications
No indication recorded.