drugset / Trial / NCT02127398

Stool Transplants to Treat Refractory Clostridium Difficile Colitis

NCT02127398

Phase 2 Recruiting 77 enrolled Duke University
NaSingle-groupOpen-labelTreatment

Summary

It has been shown that restoration of the normal makeup of the bowel bacterial population is the most effective way to treat recurrent colitis due to Clostridium difficile. Restoration of the normal bowel bacterial population is best done by transplanting stool from a healthy donor. The investigators wish to transplant stool from healthy donors to treat recurrent C. difficile colitis by incorporating the stool into capsules that are administered by the oral route.

Timeline

Start
2016-04
Primary completion
2026-05
Completion
2026-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Fecal Microbiota Other / unclassified Oral