Unrelated HSCT in Patients With Fanconi Anemia

Summary

The protocol is designed for the compassionate treatment of patients with Fanconi Anemia who do not have an HLA-matched sibling donor. The purpose of this study is to determine the likelihood of engraftment in Fanconi Anemia patients using total body irradiation (TBI), cyclophosphamide (CY), fludarabine (FLU) and antithymocyte globulin (ATG) followed by an unrelated donor hematopoietic cell transplant with T-cell depletion using the CliniMACS device.

Timeline

Start

2011-03

Primary completion

2016-03

Completion

2016-03

Outcome

Outcome not reported

Stopped (Enrollment): “Study was stopped due to non-enrollment of subjects due to rarity of disease.”

Drugs

Indications