A Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole

Phase 1 Completed 24 enrolled Astellas Pharma Global Development, Inc. Basilea Pharmaceutica International Ltd · collab

RandomizedParallel-groupOpen-labelBasic science

Summary

The purpose of this study is to assess the effect of multiple doses of esomeprazole on the pharmacokinetics of isavuconazole. In addition, safety and tolerability of isavuconazole alone and in combination with esomeprazole will be assessed

Timeline

Start: 2014-01
Primary completion: 2014-02
Completion: 2014-02

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Esomeprazole	Small molecule	—	Oral
Subject	Isavuconazole	Small molecule	—	Oral

Indications

No indication recorded.