drugset / Trial / NCT02130414

PK, Safety & Tolerability of CyCol® Versus Sandimmune® in Healthy Subjects

NCT02130414

Phase 1 Completed 48 enrolled Sigmoid Pharma
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The aim of this Phase I, single centre, multi stage study is to evaluate the safety, tolerability, pharmacokinetics and relative colonic mucosal concentrations of cyclosporine capsules (CyCol®) compared to intravenous cyclosporine in healthy male volunteers.

Timeline

Start
2014-07
Primary completion
2015-01
Completion
2015-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cyclosporine Peptide 2 mg/kg Intravenous
Comparator Cyclosporine Peptide 37.5 mg Intravenous
Comparator Cyclosporine Peptide 75 mg Intravenous
Comparator Cyclosporine Peptide 150 mg Intravenous

Indications

No indication recorded.