drugset / Trial / NCT02133911

A Pilot Trial of Ranolazine to Treat Patients With Dilated Cardiomyopathy

NCT02133911

Phase 2 Completed 10 enrolled University Medical Centre Ljubljana
RandomizedParallel-groupSingle-blindTreatment

Summary

Recent data suggest that areas of fibrosis and hibernating myocardium develop in patients with non ischemic dilated cardiomyopathy. Ranolazine is a new drug, developed to releave symptoms of angina in patients with stable coronary disease that is not suitable for surgical or percutaneous revascularization. It has been shown that in patients with stable coronary disease Ranolazine improves myocardial perfusion as shown with myocardial nuclear imaging. The aim of this trial is to evaluate effects of ranolazine on myocardial perfusion in patients with dilated cardiomyopathy.

Timeline

Start
2014-05-01
Primary completion
2015-12-15
Completion
2016-04-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Ranolazine Small molecule 750 mg