drugset / Trial / NCT02134964
Phase 1 Safety and PK Study of OLT1177 Capsules
RandomizedSingle-groupQuadruple-blindBasic science
Summary
This study is a randomized, placebo-controlled, sequential ascending-dose study of healthy volunteers after administration of single or multiple dose(s) of investigational drug (OLT1177 Caps or Placebo Caps). A total of 36 subjects will be enrolled across 6 cohorts, and subjects in each cohort will be randomized in a ratio of 5 active to 1 placebo.
Timeline
- Start
- 2014-06
- Primary completion
- 2014-12
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dapansutrile | Small molecule | 100 mg | Oral |
| Subject | Dapansutrile | Small molecule | 300 mg | Oral |
| Subject | Dapansutrile | Small molecule | 1000 mg | Oral |
Indications
No indication recorded.