drugset / Trial / NCT02135159

Patients With Brain Metastases From HER2-positive Breast Cancer

NCT02135159

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the optimal sequences of combined trastuzumab emtansine (T-DM1) and whole-brain radiotherapy in patients presenting brain metastases from HER2-positive breast cancer in terms of acute toxicities and blood/cerebrospinal fluid T-DM1 pharmacokinetics.

Timeline

Start
2014-02
Primary completion
2017-02
Completion
2017-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Trastuzumab emtansine Other / unclassified Intravenous