Countermeasures to Reduce Sensorimotor Impairment and Space Motion Sickness Resulting From Altered Gravity Levels

Phase 4 Completed 30 enrolled [email protected] Massachusetts Institute of Technology · collab National Space Biomedical Research Institute · collab

RandomizedCrossoverDouble-blindBasic science

Summary

The investigators will study adaptation of motion perception and manual control in altered gravity, including the effects of a drug (promethazine). The investigators will also study whether promethazine affects motion perceptual thresholds.

Timeline

Start: 2014-06
Primary completion: 2016-12
Completion: 2016-12

Publications

Results Diaz-Artiles A, Priesol AJ, Clark TK, Sherwood DP, Oman CM, Young LR, Karmali F. The Impact of Oral Promethazine on Human Whole-Body Motion Perceptual Thresholds. J Assoc Res Otolaryngol. 2017 Aug;18(4):581-590. doi: 10.1007/s10162-017-0622-z. Epub 2017 Apr 24.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Promethazine	Small molecule	25 mg	Oral

Countermeasures to Reduce Sensorimotor Impairment and Space Motion Sickness Resulting From Altered Gravity Levels

Summary

Timeline

Publications

Drugs

Indications