Prevention of Delayed Graft Function Using Eculizumab Therapy (PROTECT Study)

Summary

The purpose of this study was to determine if eculizumab is safe and could be used to prevent delayed graft function (DGF) following kidney transplantation.

Timeline

Start

2014-08-21

Primary completion

2016-11-22

Completion

2016-11-22

Outcome

Missed primary endpoint

registry analysis (superiority test); Eculizumab vs Placebo; p = 0.3983; Odds Ratio (OR) 0.81 (95% CI 0.49 to 1.33); Regression, Logistic NCT02145182 ↗

Drugs

Indications

No indication recorded.