drugset / Trial / NCT02147535
Impact of CES1 Genotype on Metabolism of Methylphenidate
Phase 4
Completed
78 enrolled
Bispebjerg Hospital
Duke University · collabMental Health Centre Sct. Hans (Denmark) · collabThe Leiden Academic Center for Drug Research (LACDR) · collabThe Ministry of Science, Technology and Innovation, Denmark · collabUniversity of Copenhagen · collab
NaSingle-groupOpen-labelBasic science
Summary
The purpose of this study is to determine whether differences in the gene coding for the liver enzyme carboxylesterase 1 (CES1) means differences in the metabolism of methylphenidate, a CES1 dependent drug.
Timeline
- Start
- 2014-03
- Primary completion
- 2014-08
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylphenidate | Small molecule | 10 mg | — |