drugset / Trial / NCT02150733
Pharmacokinetics of Tivantinib in Subjects With Advanced Solid Tumors and Hepatic Impairment
Non-randomizedSingle-groupOpen-labelTreatment
Summary
This is a multi-center, open-label, Phase 1 study to evaluate the impact of hepatic impairment on the pharmacokinetics of Tivantinib in cancer subjects with varying degrees of hepatic function, from normal to severely impaired.
Timeline
- Start
- 2014-04
- Primary completion
- 2015-12
- Completion
- 2016-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tivantinib | Small molecule | 120 mg | Oral |
| Subject | Tivantinib | Small molecule | 360 mg | Oral |