drugset / Trial / NCT02150733

Pharmacokinetics of Tivantinib in Subjects With Advanced Solid Tumors and Hepatic Impairment

NCT02150733

Phase 1 Completed 29 enrolled Daiichi Sankyo Medpace, Inc. · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a multi-center, open-label, Phase 1 study to evaluate the impact of hepatic impairment on the pharmacokinetics of Tivantinib in cancer subjects with varying degrees of hepatic function, from normal to severely impaired.

Timeline

Start
2014-04
Primary completion
2015-12
Completion
2016-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Tivantinib Small molecule 120 mg Oral
Subject Tivantinib Small molecule 360 mg Oral

Indications