Comparison of Treatment Modalities in Poor Responders Undergoing IVF

Completed 80 enrolled Ercan Bastu

RandomizedParallel-groupOpen-labelTreatment

Summary

The accurate identification and efficient management of poor responders remains one of the most enigmatic challenges in assisted reproductive technology (ART). The investigators study will compare the letrozole/antagonist protocol to the hMG/antagonist protocol in women who poor responders.

Timeline

Start: 2014-06
Primary completion: 2015-08
Completion: 2015-08

Publications

Background Ferraretti AP, La Marca A, Fauser BC, Tarlatzis B, Nargund G, Gianaroli L; ESHRE working group on Poor Ovarian Response Definition. ESHRE consensus on the definition of 'poor response' to ovarian stimulation for in vitro fertilization: the Bologna criteria. Hum Reprod. 2011 Jul;26(7):1616-24. doi: 10.1093/humrep/der092. Epub 2011 Apr 19.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Letrozole	Other / unclassified	5 mg	—
Comparator	human chorionic gonadotropin	Protein / enzyme biologic	150 iu	—
Comparator	human chorionic gonadotropin	Protein / enzyme biologic	300 iu	—

Indications

No indication recorded.