drugset / Trial / NCT02159950

Sipuleucel-T With or Without Tasquinimod in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

NCT02159950

RandomizedParallel-groupOpen-labelTreatment

Summary

This randomized phase II trial studies how well sipuleucel-T with or without tasquinimod works in treating patients with hormone-resistant prostate cancer that has spread to other parts of the body. Vaccines made from a person's tumor cells and white blood cells may help the body build an effective immune response to kill tumor cells. Tasquinimod may stop the growth of prostate cancer by blocking the growth of new blood vessels necessary for tumor growth. It is not yet known whether sipuleucel-T is more effective with or without tasquinimod in treating prostate cancer.

Timeline

Start
2015-01
Primary completion
2015-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Sipuleucel-T Cell therapy Intravenous
Subject Tasquinimod Small molecule Oral