drugset / Trial / NCT02161510
Safety, Pharmacokinetics, and Pharmacodynamics of MK-2248 in Participants With Hepatitis C (MK-2248-002)
RandomizedSingle-groupOpen-labelTreatment
Summary
The objective of this study is to identify a safe dose of MK-2248 in participants with Hepatitis C Virus (HCV) that mediates at least a 3 log10 reduction in viral load (VL) from baseline. It is anticipated that once-daily administration of a safe and well tolerated dose of MK-2248 will reduce VL by at least 3 log10 IU/mL.
Timeline
- Start
- 2014-07
- Primary completion
- 2014-11
- Completion
- 2015-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MK-2248 | Unknown | 200 mg | Oral |
| Subject | MK-2248 | Unknown | 800 mg | Oral |