drugset / Trial / NCT02161510

Safety, Pharmacokinetics, and Pharmacodynamics of MK-2248 in Participants With Hepatitis C (MK-2248-002)

NCT02161510 ↗

Phase 1 Completed 13 enrolled Merck Sharp & Dohme LLC
RandomizedSingle-groupOpen-labelTreatment

Summary

The objective of this study is to identify a safe dose of MK-2248 in participants with Hepatitis C Virus (HCV) that mediates at least a 3 log10 reduction in viral load (VL) from baseline. It is anticipated that once-daily administration of a safe and well tolerated dose of MK-2248 will reduce VL by at least 3 log10 IU/mL.

Timeline

Start
2014-07
Primary completion
2014-11
Completion
2015-04

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-2248 Unknown 200 mg Oral
Subject MK-2248 Unknown 800 mg Oral