Study of Beet Juice for Patients With Sickle Cell Anemia
Summary
The investigators hypothesize that increasing plasma nitrite using dietary nitrate will improve platelet function and red cell deformability and decrease MCHC in patients with sickle cell disease. The investigators will test this hypothesis through administration of daily intake of beetroot juice (Unbeetable - Performance Drink) to patients with sickle cell disease for 28 days. The investigators will evaluate the safety of daily beet root juice intake in patients with sickle cell disease. In addition, the investigators will measure MCHC, red cell deformability, and platelet function (activation and aggregation) in response to daily intake of beet root juice in this patient population.
Timeline
- Start
- 2014-09
- Primary completion
- 2019-02
- Completion
- 2019-04
Outcome
Outcome not reported
Stopped (Enrollment): “Enrollment was very slow. Hope to reopen as multi-site study”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Beetroot Juice | Other / unclassified | 8 unknown | Oral |