drugset / Trial / NCT02162303

Colchicine in Vascular Inflammation Assessed With PET Imaging

NCT02162303

Phase 2 Completed 106 enrolled Montreal Heart Institute
RandomizedParallel-groupQuadruple-blindSupportive care

Summary

The purpose of this trial is to assess the effects of colchicine on vascular inflammation measured by (FDG)-PET imaging in patients with atherosclerotic vascular disease. This effect will also be measured by soluble plasma biomarkers. Finally, an optional pharmacogenomic investigation will be performed to identify genetic biomarkers of patient response.

Timeline

Start
2014-05
Primary completion
2015-07
Completion
2016-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Colchicine Small molecule 0.6 mg