drugset / Trial / NCT02162355
Multiple Ascending Dose Study of GLPG0634 in Japanese and Caucasian Healthy Subjects
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this multiple ascending dose study is to characterize the safety, tolerability, and the amount of GLPG0634 present in the blood and urine (pharmacokinetics) of once daily oral administrations of GLPG0634 at 3 different dose levels for 10 days in Japanese healthy subjects. Furthermore, the study will compare the safety, tolerability, pharmacokinetics, and effects of GLPG0634 on mechanism of action-related parameters in the blood (pharmacodynamics) of once daily oral administrations of GLPG0634 given at one dose level for 10 days in Japanese vs Caucasian healthy subjects.
Timeline
- Start
- 2014-06
- Primary completion
- 2014-09
- Completion
- 2014-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Filgotinib | Small molecule | 50 mg | Oral |
| Subject | Filgotinib | Small molecule | 100 mg | Oral |
| Subject | Filgotinib | Small molecule | 200 mg | Oral |
Indications
No indication recorded.