drugset / Trial / NCT02169453
Pharmacokinetic-pharmacodynamic Interaction Between Each of Three Different Single Doses of BIA 9-1067 and a Single-dose of Controlled-release 100/25 mg Levodopa/Carbidopa
RandomizedCrossoverDouble-blindTreatment
Summary
To investigate the effect of three single oral doses of BIA 9-1067 (25 mg, 50 mg and 100 mg) on the levodopa pharmacokinetics when administered in combination with a single-dose of controlled-release levodopa/carbidopa 100/25 mg (Sinemet® CR 100/25)
Timeline
- Start
- 2008-10
- Primary completion
- 2009-01
- Completion
- 2009-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Opicapone | Small molecule | 25 mg | Oral |
| Subject | Opicapone | Small molecule | 50 mg | Oral |
| Subject | Opicapone | Small molecule | 100 mg | Oral |
| Background | Levodopa | Small molecule | — | — |