drugset / Trial / NCT02169479
Pharmacokinetic-pharmacodynamic Interaction Between Each of Three Diferente Single Doses of BIA 9-1067 and a Single-dose of Immediate-release 100/25 mg Levodopa/Carbidopa
RandomizedCrossoverDouble-blindTreatment
Summary
To investigate the effect of three single oral doses of BIA 9-1067 (25 mg, 50 mg and 100 mg) on the levodopa pharmacokinetics when administered in combination with a single-dose of immediate-release levodopa/carbidopa 100/25 mg (Sinemet® 100/25)
Timeline
- Start
- 2008-09
- Primary completion
- 2008-12
- Completion
- 2008-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Opicapone | Small molecule | 25 mg | Oral |
| Subject | Opicapone | Small molecule | 50 mg | Oral |
| Subject | Opicapone | Small molecule | 100 mg | Oral |
| Subject | levodopa/carbidopa | Unknown | 25 mg | — |
| Subject | levodopa/carbidopa | Unknown | 100 mg | — |