drugset / Trial / NCT02170246
Analysis of Telmisartan Administered With Antiretroviral Therapy (ART) in Patients With Acute HIV Infection
Phase 1
Completed
21 enrolled
Yale University
National Institute of Mental Health (NIMH) · collabNational Institute of Neurological Disorders and Stroke (NINDS) · collabSEARCH Research Foundation · collabUniversity of California, San Francisco · collabUniversity of Hawaii · collabWalter Reed Army Institute of Research (WRAIR) · collab
RandomizedParallel-groupDouble-blindOther
Summary
This research project will study whether the drug telmisartan administered in conjunction with antiretroviral therapy (ART) will help reduce nervous system infection with HIV. The investigators are studying the effect of this treatment in people who have contracted HIV infection within the past three weeks, and thus have a form of HIV called acute HIV infection. The investigators will measure biological markers of immune activation in the blood and cerebrospinal fluid to see if telmisartan may reduce the spread of HIV reservoirs in affected patients.
Timeline
- Start
- 2015-01-28
- Primary completion
- 2018-06-13
- Completion
- 2018-06-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Telmisartan | Other / unclassified | 80 mg | — |