drugset / Trial / NCT02170805

Bioavailability of BIBR 1048 MS Single Doses With or Without Pantoprazole in Healthy Subjects

NCT02170805

Phase 1 Completed 24 enrolled Boehringer Ingelheim
RandomizedCrossoverOpen-labelTreatment

Summary

The pharmacokinetics of 50 mg BIBR 1048 administered as two newly developed capsule formulation using melt extrusion technology was assessed in two separate, single dose, 3-way crossover, open design, randomised studies. The 3-way crossover treatments included administration of the tartaric acid solution of 50 mg BIBR 1048, the capsule formulation A or B and administration of the capsules with coadministration of pantoprazole.

Timeline

Start
2001-04
Primary completion
2001-06
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Dabigatran etexilate Unknown 50 mg Oral
Subject Pantoprazole Other / unclassified 40 mg

Indications

No indication recorded.