drugset / Trial / NCT02172417
Tiotropium in Combination With Concomitant Cimetidine or Ranitidine in Healthy Male and Female Subjects
RandomizedCrossoverOpen-labelTreatment
Summary
Study to investigate the effect of an inhibition of the renal cationic drug transporter on single dose pharmacokinetics of intravenous tiotropium in subjects in an age close to typical Chronic Obstructive Pulmonary Disease (COPD) population
Timeline
- Start
- 2000-07
- Primary completion
- 2000-11
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cimetidine | Small molecule | 400 mg | Oral |
| Subject | Ranitidine | Unknown | 300 mg | Oral |
| Subject | Tiotropium | Other / unclassified | 14.4 ug | Intravenous |
Indications
No indication recorded.