drugset
drugset / Trial / NCT02174250

The Effect of Rifampin on the Metabolism of Istradefylline in Healthy Volunteers.

NCT02174250 ↗

Phase 1 Completed 20 enrolled Kyowa Kirin, Inc. Kyowa Hakko Kirin Pharma, Inc. · collab
Non-randomizedCrossoverOpen-labelBasic science

Summary

The purpose of this study is to test whether Rifampin affects blood levels of istradefylline in humans. Rifampin could possibly decrease istradefylline levels.

Timeline

Start
2014-06
Primary completion
2014-08
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Istradefylline Small molecule 40 mg —
Subject Rifampin Small molecule 300 mg —

Indications

Parkinson disease