drugset / Trial / NCT02176486

Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of Ixazomib in Lupus Nephritis (LN)

NCT02176486

Phase 1 Terminated 12 enrolled Takeda
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to characterize the safety and tolerability of ixazomib when administered as multiple oral doses at escalating dose levels in participants with lupus nephritis.

Timeline

Start
2014-06-09
Primary completion
2017-03-30
Completion
2018-01-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Ixazomib Unknown 0.5 mg Oral
Subject Ixazomib Unknown 2 mg Oral
Subject Ixazomib Unknown 3 mg Oral
Subject Ixazomib Unknown 4 mg Oral

Indications