Comparative Study of Hemodynamic Changes Caused by Diazepam and Midazolam During Third Molar Surgery

Summary

Objective: The aim of the present study was to compare hemodynamic changes using 7.5 mg of midazolam and 10.0 mg of diazepam during the surgical removal of symmetrically positioned third molars. Study design: A prospective, randomized, double-blind, clinical trial was carried out involving 120 patients divided in three groups: Group 1 (diazepam and placebo), Group 2 (midazolam and placebo) and Group 3 (diazepam and midazolam). Each subject underwent two surgeries on separate occasions under local anesthesia.

Timeline

Start

2011-01

Primary completion

2012-07

Completion

2012-09

Drugs

Indications