Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasis

Phase 4 Completed 240 enrolled Peking University Shenzhen Hospital Bayer · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

The study is focused to prove that the efficacy and safety of Clotrimazole vaginal tablet vs Fluconazole for the treatment of severe vulvovaginal candidiasis

Timeline

Start: 2014-07
Primary completion: 2015-09
Completion: 2015-09

Publications

Results Zhou X, Li T, Fan S, Zhu Y, Liu X, Guo X, Liang Y. The efficacy and safety of clotrimazole vaginal tablet vs. oral fluconazole in treating severe vulvovaginal candidiasis. Mycoses. 2016 Jul;59(7):419-28. doi: 10.1111/myc.12485. Epub 2016 Apr 13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Clotrimazole	Unknown	500 mg	Other
Comparator	Fluconazole	Small molecule	150 mg	Oral

Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasis

Summary

Timeline

Publications

Drugs

Indications