Pulmonary Function and Interscalene Block

Completed 50 enrolled University of Pennsylvania

RandomizedParallel-groupDouble-blindTreatment

Summary

The objective of our study is to compare the degree of phrenic nerve blockade after interscalene block using 0.1% ropivacaine or 0.2% ropivacaine. Our hypothesis is that using a lower concentration of local anesthetic will result in lesser degree of phrenic nerve block. 40 patients will be enrolled. Half will receive the block with 0.1% ropivacaine and half with 0.2% ropivacaine. Phrenic nerve and diaphragm function will be assessed by bedside spirometry and ultrasound visualization.

Timeline

Start: 2014-07
Primary completion: 2016-02
Completion: 2016-02

Publications

Wong AK, Keeney LG, Chen L, Williams R, Liu J, Elkassabany NM. Effect of Local Anesthetic Concentration (0.2% vs 0.1% Ropivacaine) on Pulmonary Function, and Analgesia After Ultrasound-Guided Interscalene Brachial Plexus Block: A Randomized Controlled Study. Pain Med. 2016 Dec;17(12):2397-2403. doi: 10.1093/pm/pnw057. Epub 2016 Apr 13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ropivacaine	Other / unclassified	0.1 %	—
Comparator	Ropivacaine	Other / unclassified	0.2 %	—

Indications

No indication recorded.