drugset / Trial / NCT02181465
Study to Assess Safety and Tolerability of G17DT in Patients With Colorectal Adenocarcinoma.
Non-randomizedSingle-groupOpen-labelTreatment
Summary
Pancreatic, gastric, and colorectal cancers have all been shown to overexpress the gastrin gene and to be sensitive to the trophic effects of the gastrin in animal models. The hypothesis of this study is that G17DT will elicit specific and high-affinity antibodies that will bind gastrin-17, thus preventing the trophic activity of cancer cells.
Timeline
- Start
- 1993-10
- Primary completion
- 1994-05
- Completion
- 1994-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | G17DT Immunogen | Vaccine | 2 mg | Intramuscular |