drugset / Trial / NCT02181998

A Trial on Efficacy and Safety of Full Dose Tenecteplase Combined With Unfractionated Heparin (UFH) or Enoxaparin in Acute Myocardial Infarction (AMI) in the Prehospital Setting

NCT02181998

Phase 3 Completed 1606 enrolled Boehringer Ingelheim
RandomizedParallel-groupOpen-labelTreatment

Summary

The primary objective of ASSENT 3 Plus (the same as for ASSENT 3) was to evaluate the safety and efficacy of full dose tenecteplase combined with unfractionated heparin (UFH, group A) and full dose tenecteplase combined with enoxaparin (ENOX, group B). An additional objective in ASSENT 3 Plus was to describe the different time intervals in the prehospital phase.

Timeline

Start
2000-07
Primary completion
2002-08
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Enoxaparin sodium Other / unclassified
Subject Tenecteplase Protein / enzyme biologic
Comparator Unfractioned Heparin Unknown

Indications