Metabolism and Pharmacokinetics of [14C]-BIBF 1120 in Healthy Male Volunteers

Summary

To assess the metabolic profile, to obtain the mass balance after oral administration, to determine the concentration of \[14C\]-radioactivity in blood cells, plasma, urine and faeces, to determine BIBF 1120 and BIBF 1202 concentrations in plasma, urine, and faeces, if feasible, to determine the protein binding of \[14C\]-radioactivity, to determine the pharmacokinetics of BIBF 1120, BIBF 1202 and total radioactivity after a single oral administration of \[14C\]-BIBF 1120 in healthy volunteers

Timeline

Start

2005-10

Primary completion

2005-11

Completion

—

Drugs

Indications

No indication recorded.