drugset / Trial / NCT02183779
PORH and Response to Cold in Raynaud's Phenomenon.
RandomizedParallel-groupQuadruple-blindBasic science
Summary
The main objective of the study is to determine if implication of epoxy-eicosatriénoïc acids (EETs) and NO during cutaneous post-occlusive hyperemia differs between patients with Raynaud phenomena and healthy volunteers, by studying hyperaemic postocclusive response after microinjection of fluconazole and L-NMMA at the dorsal side of the fingers.
Timeline
- Start
- 2014-06
- Primary completion
- 2016-10
- Completion
- 2017-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluconazole | Small molecule | — | Other |
| Subject | L-NMMA | Unknown | — | Other |