drugset / Trial / NCT02185209
Surgical Treatment of Peri-implantitis With and Without Systemically Adjunctive Antibiotics
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to investigate if the use of systemic adjunctive antibiotics in the treatment of periimplantitis is needed.
Timeline
- Start
- 2015-03
- Primary completion
- 2022-05-27
- Completion
- 2022-05-27
Publications
- Riben Grundstrom C, Lund B, Bostanci N, Silbereisen A, Pennhag A, Koistinen IS, Zha Y, Damdimopoulos A, Belibasakis GN, Hultin M. Systemic Antibiotics in the Surgical Treatment of Peri-Implantitis: Impact on the Salivary Microbiome. J Clin Periodontol. 2026 May 25. doi: 10.1111/jcpe.70143. Online ahead of print.
- Riben Grundstrom C, Lund B, Kampe J, Belibasakis GN, Hultin M. Systemic antibiotics in the surgical treatment of peri-implantitis: A randomized placebo-controlled trial. J Clin Periodontol. 2024 Aug;51(8):981-996. doi: 10.1111/jcpe.13994. Epub 2024 May 3.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 500 mg | — |
| Comparator | Metronidazole | Small molecule | 400 mg | — |
| Comparator | Penicillin V | Small molecule | 1600 mg | — |