Combination of Continuous Femoral Block and Intravenous Parecoxib For Postoperative Analgesia After Total Knee Arthroplasty

Phase 2/3 Completed 90 enrolled Asklepieion Voulas General Hospital

RandomizedParallel-groupQuadruple-blind

Summary

Combination of continuous femoral block with parEcoxib vs placebo. Investigation of morphine consumption, opioid sparing effects, VAS pain scores, haemodynamics, Anxierty scores, transfusion requirements , Range of motion and rehabilitation parameters between two groups

Timeline

Start: 2009-01
Primary completion: 2011-09
Completion: 2014-02

Publications

Sarridou DG, Chalmouki G, Braoudaki M, Siafaka I, Asmatzi C, Vadalouka A. Parecoxib Possesses Anxiolytic Properties in Patients Undergoing Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Clinical Study. Pain Ther. 2016 Jun;5(1):55-62. doi: 10.1007/s40122-016-0046-1. Epub 2016 Feb 9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Parecoxib	Small molecule	40 mg	Intravenous
Background	Ropivacaine	Other / unclassified	0.2 %	Other

Indications

No indication recorded.