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drugset / Trial / NCT02186652

PK Study With Pantoprazole in Obese Children and Adolescents

NCT02186652 ↗

Phase 1 Completed 41 enrolled Phillip Brian Smith The Emmes Company, LLC · collab

NaSingle-groupOpen-labelBasic science

Summary

Multicenter, comparative single-dose pharmacokinetic (PK) study

Timeline

Start: 2014-06-04
Primary completion: 2015-09-13
Completion: 2015-09-13

Publications

Shakhnovich V, Smith PB, Guptill JT, James LP, Collier DN, Wu H, Livingston CE, Zhao J, Kearns GL; Best Pharmaceuticals for Children Act - Pediatric Trials Network. Obese Children Require Lower Doses of Pantoprazole Than Nonobese Peers to Achieve Equal Systemic Drug Exposures. J Pediatr. 2018 Feb;193:102-108.e1. doi: 10.1016/j.jpeds.2017.10.011.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Pantoprazole	Other / unclassified	1.2 mg/kg	Oral

Indications