drugset / Trial / NCT02188303

A Study of LY2944876 in Healthy Japanese and Non-Japanese Participants

NCT02188303

Phase 1 Terminated 48 enrolled OPKO Health, Inc.
RandomizedSequentialDouble-blindBasic science

Summary

LY2944876 is an investigative drug for the treatment of Type 2 Diabetes Mellitus. Part A of the study will assess the safety and tolerability of single doses of LY2944876 in Japanese participants. Participation is expected to last up to about 7 weeks, not including screening. Part B of the study will investigate the safety and tolerability of multiple doses of LY2944876 in non Japanese participants. Participation is expected to last up to about 8 weeks, not including screening. All doses will be administered as injections into the fatty layer just beneath the skin. Screening is required within 28 days prior to the start of the study. All participants will attend a post study safety assessment approximately 6 weeks after their final dose.

Timeline

Start
2014-07
Primary completion
2014-12
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject PEGAPAMODUTIDE Protein / enzyme biologic 10 mg Subcutaneous
Subject PEGAPAMODUTIDE Protein / enzyme biologic 40 mg Subcutaneous
Subject PEGAPAMODUTIDE Protein / enzyme biologic 80 mg Subcutaneous

Indications

No indication recorded.